Probiotics and Menstrual Cramps: A Gut Feeling - MenstrEaze: You Deserve Better Periods

Probiotics and Menstrual Cramps: A Gut Feeling

It's becoming increasingly clear that the health of our gut/microbiome significantly influences our overall well-being and quality of life. From aiding in digestion to strengthening our immune system and even impacting our mood, the gut plays a multifaceted role in maintaining health. Among these, a particularly intriguing aspect is the potential relationship between gut health, more specifically the role of probiotics, and menstrual health. This article delves into the complex world of probiotics and their potential impact on menstrual cramps. 

What are Probiotics and Their Role in Gut Health?

Probiotics are live nonpathogenic microorganisms administered to improve microbial balance, particularly in the gastrointestinal tract. They are often dubbed as 'friendly' or 'good' bacteria because they help keep our gut healthy. They consist of Saccharomyces boulardii yeast or lactic acid bacteria, such as Lactobacillus and Bifidobacterium species, and are regulated as dietary supplements and foods. Probiotics are generally considered safe and well tolerated, with bloating and flatulence occurring most frequently.

Probiotics exert their beneficial effects through various mechanisms, including lowering intestinal pH, decreasing colonization and invasion by pathogenic organisms, and modifying the host immune response. Currently, there is no consensus about the minimum number of microorganisms that must be ingested to obtain a beneficial effect; however, a probiotic should typically contain several billion microorganisms to increase the chance that adequate gut colonization will occur.

Our gut houses trillions of bacteria, both good and bad, collectively known as the gut microbiota. When this microbial balance is disrupted - by factors such as poor diet, stress, or antibiotic use - it can lead to dysbiosis, a condition associated with numerous health issues, including gastrointestinal disorders, obesity, mental health problems, and autoimmune diseases.

Probiotics can help restore this microbial balance. They can inhibit the growth of harmful bacteria, enhance gut barrier function, and modulate the immune system, thereby promoting overall gut health. 

However, probiotics should be used cautiously in patients who are critically ill or severely immunocompromised or those with central venous catheters since systemic infections may rarely occur. Bacteria-derived probiotics should be separated from antibiotics by at least two hours.

The Gut-Hormone Connection and Menstrual Cramps

The gut and the endocrine system, responsible for hormone production, are closely linked. The gut microbiota can influence hormone levels in the body, including those involved in the menstrual cycle, such as estrogen. This influence occurs through the gut's role in metabolizing and recycling hormones.

Estrogen, a key hormone regulating the menstrual cycle, can stimulate the production of prostaglandins, hormone-like substances that cause the uterus to contract during menstruation, leading to menstrual cramps. If the gut microbiota is imbalanced, it can disrupt estrogen metabolism, potentially leading to higher prostaglandin levels and more intense menstrual cramps.

For example, scientists have shown that the administration of certain probiotic led to modulation of gut flora composition and a rise in the hormone GLP-1.

The Benefits of Probiotic Supplementation for Menstrual Health

Given the crucial role of gut health in hormone regulation, it's plausible that improving gut health through probiotics could help alleviate menstrual cramps. While research in this specific area is relatively limited, several studies suggest potential benefits of probiotics for menstrual health.

Probiotics may help reduce menstrual pain by modulating the immune system, reducing inflammation, and improving hormonal balance. Some studies have shown that certain strains of probiotics can reduce the production of prostaglandins, potentially easing menstrual cramps.

Furthermore, probiotics can also help manage other menstrual-related issues. For example, they may improve digestive symptoms often accompanying menstruation, such as bloating and constipation, by promoting gut motility and reducing gut inflammation. Besides, there are also researchers demonstrating that using symbiotic and probiotic in women with polycystic ovary syndrome improve hormonal and inflammatory indices in PCOS patients. 

Incorporating Probiotic-Rich Foods into the Diet

While probiotic supplements can be a convenient way to increase probiotic intake, they're not the only option. Many foods are naturally rich in probiotics and can be easily incorporated into the diet.

Yogurt is one of the most well-known probiotic foods. Look for yogurt labeled with "live and active cultures" to ensure it contains probiotics. Other fermented dairy products, like kefir, a drink made from fermented milk, also contain high amounts of probiotics.

Fermented vegetables, such as sauerkraut, pickles and kimchi, are also great sources of probiotics. Similarly, fermented soy products like tempeh, natto and miso are rich in probiotics.

Moreover, some types of cheese, such as cheddar, mozzarella, and gouda, undergo fermentation and thus contain probiotics. However, not all cheeses are probiotic-rich, so it's essential to check the labels. 

In addition to these, non-dairy fermented drinks like kombucha, a fermented tea, can also provide a good dose of probiotics. Additionally, sourdough bread, made from fermented dough, contains a type of probiotic known as Lactobacillus.

Final Thoughts

While the research on probiotics and menstrual cramps is still in its early stages, it's clear that maintaining a healthy gut microbiota plays a vital role in our overall health and well-being, including hormonal balance. Therefore, incorporating probiotics into your diet may be beneficial not only for your digestive health but also potentially for your menstrual health.

As with any dietary change, it's important to listen to your body and observe how it responds. What works for one person may not necessarily work for another, as our bodies and microbiomes are unique. And remember, while probiotics can contribute to a healthier gut, they are just one piece of the puzzle. A balanced diet, regular exercise, adequate sleep, and stress management are all equally important for maintaining good gut health and overall well-being.

Lastly, before starting any new supplementation, including probiotics, it's always advisable to consult with a healthcare provider or a registered dietitian. They can provide personalized advice based on your individual needs and circumstances.

In conclusion, while we are still uncovering the complex interplay between the gut and menstrual health, the potential of probiotics offers an exciting avenue for managing menstrual cramps. The future of probiotic research holds promise, and we look forward to more evidence elucidating the precise role of probiotics in menstrual health. 


  1. Nancy Toedter Williams, Pharm.D., BCPS, BCNSP, Probiotics, American Journal of Health-System Pharmacy, Volume 67, Issue 6, 15 March 2010, Pages 449–458.
  2. Max Norman Tandrup Lambert and others, Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial, The American Journal of Clinical Nutrition, Volume 106, Issue 3, September 2017, Pages 909–920.
  3. Yadav, Hariom, et al. "Beneficial metabolic effects of a probiotic via butyrate-induced GLP-1 hormone secretion." Journal of biological chemistry 288.35 (2013): 25088-25097.
  4. Judkins, T.C., Oula, ML., Sims, S.M. et al. The effect of a probiotic on gastrointestinal symptoms due to menstruation in healthy adult women on oral contraceptives: randomized, double-blind, placebo-controlled trial protocol. Trials 23, 481 (2022).
  5. Zakaria, Izyan Atiqah, et al. "The effect of probiotics on quality of life in women with primary dysmenorrhoea: a randomized, double-blind, placebo-controlled trial." Authorea Preprints (2020).
  6. Shamasbi, S.G., Ghanbari-Homayi, S. & Mirghafourvand, M. The effect of probiotics, prebiotics, and synbiotics on hormonal and inflammatory indices in women with polycystic ovary syndrome: a systematic review and meta-analysis. Eur J Nutr 59, 433–450 (2020). 
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